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GI Nurse Practitioner (Remote)

Oshi Health · Sioux Falls, SD

Posted October 13, 2026

Oshi Health - Sioux Falls, SD (Remote) · Statewide Telehealth (South Dakota), Sioux Falls, SD, US, 57104

Remote GI Nurse Practitioner — virtual-first digestive health care

  • Pay: $125,000 per year, plus annual bonus eligibility
  • Location: 100% remote. This posting is for Nurse Practitioners living in South Dakota.
  • Licensure: active South Dakota NP license; licensure in 2 additional states preferred (Oshi supports and reimburses cross-licensure)
  • Schedule: full-time, ~30 hours of patient care + 10 hours of documentation and admin per week, including some early-morning, evening and weekend hours

GI Expert Nurse Practitioner — Clinical

Reports To: APP Pod Lead

Licenses Currently Held: Preferred RN compact License

Employment Type: Full-Time

Role Overview

As a GI Expert Nurse Practitioner at Oshi Health, you'll deliver high-quality, virtual-first gastrointestinal care to adults with complex digestive conditions through our telemedicine platform. You'll work alongside a collaborative, multidisciplinary team with dietitians, and behavioral health specialists to provide coordinated, whole-person care that helps patients achieve lasting digestive health improvements. This role is at the heart of our mission — and your clinical expertise will directly change lives.

What You'll Do — Key Responsibilities

  • Deliver virtual patient care in alignment with Oshi's evidence-based care model, including assessment, diagnosis, and treatment planning for GI conditions with a focus on DGBIs, GERD, and IBD via video visits and chat messaging
  • Collaborate with a multidisciplinary team (GI physicians, dietitians, behavioral health specialists, and care coordinators) to implement coordinated, comprehensive care plans
  • Adhere to clinical protocols including ROME IV criteria and AGA and ACG guidelines to ensure high-quality, evidence-based care delivery
  • Document patient interactions accurately and timely within the EHR, maintaining thorough and compliant records
  • Allocate approximately 30 hours per week to direct patient care and 10 hours to documentation, meetings, and administrative responsibilities
  • This is not a traditional 9-5 role — scheduling includes a mix of early morning, evening, and weekend hours to meet patient access needs. Flexibility and willingness to work outside standard business hours is essential
  • Participate in quality improvement, clinical program development, and professional training to stay current in the field of gastrointestinal care
  • Pursue cross-licensure opportunities and maintain good standing with all relevant licenses and certifications

What We're Looking For — Qualifications & Requirements

Required

  • Current licensure as a Certified Registered Nurse Practitioner (CRNP) or Advanced Practice Registered Nurse (APRN) with a Master's or Doctoral degree in Nursing
  • Current certification by ANCC, AANP, or other qualifying agency as an Adult or Family Nurse Practitioner
  • Minimum of 3 years of experience in gastroenterology specialty in an outpatient setting
  • Ability to communicate and collaborate effectively with multidisciplinary care providers including physicians, psychologists, and registered dietitians

Preferred

  • Licensure in 2 additional states desired — candidates must be willing and able to obtain within 60 days of hire
  • Experience with or willingness to learn common administrative and clinical technologies (Zoom, Google Suite, Salesforce, Athena, or equivalent)
  • Prior experience with telehealth platforms
  • Comfort operating in an entrepreneurial or start-up environment with evolving workflows and ambiguity

Compensation & Benefits

  • Health Benefits: 90% employee premiums paid for medical, dental, and vision coverage
  • Time Off: 3 weeks paid PTO + 11 paid holidays + 1 floating holiday
  • Retirement: Eligibility to contribute to 401(k)
  • Work Style: Remote-first — work from home anywhere in the US within our approved states
  • Growth: Advanced training by GI-specialized clinicians and professional development support as we scale
  • Licensure: Cross-licensure support and reimbursement opportunities
  • Life Concierge: Dedicated personal support through Overalls

About Oshi Health

Oshi Health is a virtual digestive health practice on a mission to transform GI care. We combine compassionate, multidisciplinary care with innovative technology to help people with chronic digestive conditions get the answers and relief they deserve. When you join Oshi, you're joining a team — and a mission — that's changing what great healthcare looks like.

Oshi Health is revolutionizing GI care with a digital clinic model that provides easy, convenient access to an integrated and multidisciplinary care team that takes a whole-person approach to diagnosing, managing, and treating digestive health conditions.

We take time to get to know each patient, develop a personalized, whole-person care plan that includes identification of symptom triggers and prescription of evidence-based interventions, including medications, dietary changes, and mental health support.

For Every Oshi Team Member We Want:

  • Genuine passion for improving patient lives and transforming GI care
  • Strong communication skills and emotional intelligence
  • Comfort in a fast-paced, remote-first, mission-driven environment

Note: This job description serves as a general overview and may be subject to change based on organizational needs and requirements.

Oshi Health is an equal opportunity employer that is committed to creating a diverse work environment. To do that, we champion a workplace where each and every person is treated with dignity and respect and is valued for their unique perspective and contributions.

Oshi Health’s policy is to maintain a working environment that encourages mutual respect, promotes harmonious and congenial relationships between employees, and is free from all forms of discrimination and harassment of any employee (or applicant for employment or service provider) by anyone, including supervisors, co-workers, vendors, or clients. Harassment and discrimination in any manner or form is expressly prohibited. There is no tolerance for discrimination or unequal treatment of any kind on the basis of race, color, religion, creed, gender, sex, sexual orientation, gender identity or expression, pregnancy, sexual and reproductive health decisions, national origin, age, disability, genetic information, marital status or civil partnership/union status, familial status, military or veteran status, predisposition or carrier status, domestic violence victim status, alienage or citizenship status, unemployment status, sexual violence or stalking victim status, caregiver status, or any other characteristic protected by law.

This practice applies to all terms, conditions and privileges of employment including, but not limited to, recruitment, selection, promotion, demotion, transfer, layoff, rehire, termination of employment, development and training, compensation, benefits and retirement.

Employer

Oshi Health

Oshi Health is a virtual digestive health practice on a mission to transform GI care. Its digital clinic gives people with chronic digestive conditions easy, convenient access to an integrated, multidisciplinary care team that takes a whole-person approach to diagnosing, managing and treating digestive health.

Oshi's care teams bring together GI physicians, gastroenterology nurse practitioners, registered dietitians, behavioral health specialists and care coordinators. They treat conditions including IBS and other disorders of gut-brain interaction (DGBIs), GERD and inflammatory bowel disease. Care follows ROME IV criteria and AGA and ACG guidelines and is delivered through video visits and chat messaging.

Every patient gets time and attention. The care team learns each patient's story, identifies symptom triggers and builds a personalized plan that can combine medications, dietary changes and mental health support, helping patients find answers and lasting relief.

Oshi's clinicians work remote-first from home. Benefits include 90% of medical, dental and vision premiums paid; 3 weeks of PTO plus 11 paid holidays and a floating holiday; a 401(k); advanced training from GI-specialized clinicians; cross-licensure support and reimbursement; and a personal life concierge through Overalls.

Livability

207,795
Sioux Falls population
$211K
Avg 3-bedroom home
—
Avg high / low
Nearby cities
Brookings
48.4 mi
Pop. 23,710
Brandon
6.3 mi
Pop. 10,996
Sioux Center
45.4 mi
Pop. 8,335
Source: US Census Bureau
Annual family budget — Minnehaha County
—
Housing, food, transport, healthcare, childcare & taxes for a typical family
$211K
Avg 3-bedroom home
$1,100
Avg monthly rent
Source: EPI Family Budget Calculator
Source: Zillow
—
Avg high / low
—
Yearly rainfall
—
Sunny days / yr
Source: WeatherAPI.com
Population — ZIP 57104
26,627
Total residents
14,529
Male residents
12,098
Female residents
Age distribution
total
26,627
0-9
2,963
10-19
2,798
20-29
4,756
30-39
5,025
40-49
3,337
50-59
3,101
60-69
2,511
70-79
1,229
80+
907
Ethnicity
White
19,121
Black Or African American
2,852
American Indian Or Alaskan Native
1,576
Asian
397
Native Hawaiian Or Other Pacific Islander
7
Other
243
Two Or More
2,431
Source: US Census Bureau
25
Walk Score — Car-Dependent
29
Bike Score — Somewhat Bikeable
16
Transit Score — Minimal Transit
Source: WalkScore.com
Nearby airports
Eppley Airfield (OMA) 164.26 mi
Sioux Falls Regional Airport / Joe Foss Field (FSD) 2.24 mi
Sioux Gateway Airport / Brigadier General Bud Day Field (SUX) 84.94 mi
Watertown Regional Airport (ATY) 93.21 mi
Source: FAA database
GI Nurse Practitioner (Remote)
Oshi Health · Sioux Falls, SD