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Advanced Practice Provider (NP/PA) - Infectious Disease

Medical University of South Carolina · Columbia, SC

Posted October 19, 2026

MUSC Health Columbia Medical Center Downtown · 2435 Forest Dr, Columbia, SC, US, 29204

  • Pay: MUSC does not post a pay range for this role (competitive compensation per MUSC pay grade)
  • Employment: Full time, 40 hours/week
  • Location: MUSC Health Columbia Medical Center Downtown
  • Employer: MUSC Community Physicians (MCP)
  • MUSC Job ID: R-0000063009

MUSC Health – Columbia Medical Center Downtown is seeking a compassionate and highly skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Infectious Disease team. This is an exciting opportunity to practice in a collaborative environment focused on delivering exceptional care for patients with complex infectious diseases and conditions.

You’ll work alongside a collaborative, multidisciplinary team in a supportive environment that encourages innovation, professional growth, and work-life balance.

In this role, you will work closely with Infectious Disease physicians, hospital teams, and multidisciplinary specialists to provide comprehensive inpatient and outpatient care while contributing to improved patient outcomes and community health.

About MUSC Health – Columbia Medical Center Downtown

MUSC Health – Columbia Medical Center Downtown is a full-service, community-based hospital located in the heart of Columbia, South Carolina. As part of the nationally recognized Medical University of South Carolina health system, the downtown campus is committed to delivering high-quality, patient-centered care supported by the innovation, research, and clinical expertise of one of the nation’s leading academic medical centers.

Providers at Columbia Medical Center Downtown benefit from a collaborative culture, access to advanced clinical resources, and the opportunity to care for a diverse patient population across the Midlands region.

Required Qualifications

  • Advanced Practice Provider: Nurse Practitioner (NP) or Physician Assistant (PA)
  • Infectious Disease experience preferred, but motivated new graduates with strong clinical training are encouraged to apply
  • Strong clinical assessment and diagnostic skills
  • Passion for delivering patient-centered care in a collaborative team environment
  • Commitment to evidence-based medicine, infection prevention, and quality improvement

Position Highlights

  • Provide inpatient and outpatient Infectious Disease follow-up care
  • Evaluate and manage patients with acute and chronic infectious conditions including sepsis, bacteremia, osteomyelitis, hepatitis, and complex infections
  • Collaborate with physicians, pharmacists, nursing staff, and care management teams to develop individualized treatment plans
  • Assist with antimicrobial stewardship initiatives and infection prevention strategies
  • Participate in patient education, transitions of care, and coordination with referring providers
  • Utilize Epic EHR and integrated clinical tools to support efficient, high-quality patient care
  • Join a supportive culture that values teamwork, provider wellness, and professional development

Benefits & Resources for Providers

  • Competitive compensation and benefits
  • Employer-funded retirement plans
  • Paid occurrence malpractice coverage
  • Paid parental leave
  • Epic EHR with provider-centered optimization and robust user support
  • AI-enabled documentation and workflow tools integrated into Epic to reduce administrative burden and support clinical decision-making at the point of care
  • Team-based care models that support sustainable workloads, shared responsibility, and provider well-being

Life in Columbia, South Carolina

Discover the best of both worlds, big-city opportunity with small-town warmth.

Columbia is South Carolina’s vibrant capital city, perfectly positioned between the beautiful beaches of the Lowcountry and the majestic Blue Ridge Mountains. Enjoy top rated schools, family friendly neighborhoods, award winning restaurants, festivals, and endless outdoor adventures at Lake Murray and nearby state parks.

About MUSC

South Carolina’s leading academic health system, MUSC Health, serves patients across the state through a growing network of hospitals, clinics, and specialty services. As the clinical enterprise of the Medical University of South Carolina, MUSC Health integrates academic medicine, research, and education with a strong commitment to patient care. Providers who join MUSC Health become part of a mission-driven organization recognized for clinical excellence, innovation, and meaningful investment in providers’ success. With opportunities in both academic and community settings, MUSC Health provides the scale, resources, and infrastructure to support meaningful, long-term provider careers.

Employer

Medical University of South Carolina

MUSC Health is South Carolina's leading academic health system and the clinical enterprise of the Medical University of South Carolina in Charleston. It serves patients across the state through a growing network of hospitals, clinics and specialty services, integrating academic medicine, research and education with a strong commitment to patient care.

The MUSC Health system:

  • MUSC Health University Medical Center and the MUSC Shawn Jenkins Children's Hospital in Charleston, the state's academic medical center
  • Regional medical centers in Columbia, Florence, Orangeburg, Lancaster, Chester, Camden (Kershaw), Marion, Cades (Black River) and Mount Pleasant (East Cooper), plus MUSC Health at Tidelands on the Grand Strand
  • MUSC Hollings Cancer Center, MUSC Community Physicians and primary and specialty care practices across South Carolina

Why physicians and advanced practice providers choose MUSC Health:

  • Academic and community practice opportunities, with faculty appointments through the Medical University of South Carolina
  • Commencement and sign-on bonuses on many roles, employer-funded retirement plans and paid occurrence malpractice coverage
  • CME allowance and paid days off, paid parental leave, and Public Service Loan Forgiveness (PSLF) eligibility
  • Epic EHR with AI-enabled documentation tools
  • South Carolina living, from historic Charleston and the Lowcountry to the beaches of the Grand Strand and the Midlands

Livability

605,083
Columbia population
$187K
Avg 3-bedroom home
—
Avg high / low
Nearby cities
Sumter
35.3 mi
Pop. 68,914
Lexington
12.9 mi
Pop. 24,132
St. Andrews
6.2 mi
Pop. 20,953
Source: US Census Bureau
Annual family budget — Richland County
—
Housing, food, transport, healthcare, childcare & taxes for a typical family
$187K
Avg 3-bedroom home
$1,321
Avg monthly rent
Source: EPI Family Budget Calculator
Source: Zillow
—
Avg high / low
—
Yearly rainfall
—
Sunny days / yr
Source: WeatherAPI.com
Population — ZIP 29204
18,034
Total residents
8,491
Male residents
9,543
Female residents
Age distribution
total
18,034
0-9
1,475
10-19
2,605
20-29
3,443
30-39
1,877
40-49
1,799
50-59
1,837
60-69
2,445
70-79
1,592
80+
961
Ethnicity
White
8,016
Black Or African American
9,154
American Indian Or Alaskan Native
5
Asian
186
Native Hawaiian Or Other Pacific Islander
5
Other
114
Two Or More
554
Source: US Census Bureau
31
Walk Score — Car-Dependent
44
Bike Score — Somewhat Bikeable
29
Transit Score — Some Transit
Source: WalkScore.com
Nearby airports
Charlotte Douglas International Airport (CLT) 81.92 mi
Columbia Metropolitan Airport (CAE) 9.27 mi
Augusta Regional At Bush Field (AGS) 71.76 mi
Florence Regional Airport (FLO) 73.80 mi
Greenville Spartanburg International Airport (GSP) 91.68 mi
Concord-Padgett Regional Airport (USA) 95.31 mi
Source: FAA database
Advanced Practice Provider (NP/PA) - Infectious Disease
Medical University of South Carolina · Columbia, SC